BACKGROUND:The precision of the metaphase-anaphase transition ensures stable genetic inheritance. The spindle checkpoint blocks anaphase onset until the last chromosome biorients at metaphase plate. then the bonds between sister chromatids are removed and disjoined chromatids segregate to the spindle poles. But. https://www.spidertattooz.com/Orly-Nail-Lacquer-Impressions-Collection-p28870/